Other Ingredients: Gelatin, Rice Powder, Shellfish (shrimp, crab, lobster, crayfish).
Directions: Take 3 capsules daily as a dietary supplement or as directed by a healthcare professional.
Do not take this product if you have an allergy to shellfish.
Glucosamine and chondroitin are two molecules that make up the type of cartilage found within joints. Glucosamine is a part of a molecule called a glycosaminoglycan-this molecule is used in the formation and repair of cartilage and Chondroitin is the most abundant glycosaminoglycan in cartilage and is responsible for the resiliency of cartilage. Inside your joints, cartilage undergoes a constant process of breakdown and repair. To be properly repaired, the building blocks of cartilage must be present and available. Using glucosamine and chondroitin joint supplements provide the cartilage building blocks to be available for cartilage repair.
MSM (methylsulfonylmethane) is formed using dimethylsulfoxide (DMSO), an organic form of sulfur which provides a vital building block of joints, cartilage, skin, hair and nails. Published, peer-reviewed clinical research in the U.S. has shown MSM is safe and effective in increasing joint comfort and supporting a normal range of motion.
In Ayurvedic medicine, Boswellia serrate has been used for hundreds of years for treating arthritis. The resin extracted from the herb is widely recognized as a treatment for arthritis due to its anti-inflammatory and pain-relieving properties. Scientific studies have found that the most biologically active component in the herb is 3-O-acetyl-11-keto-beta-boswellic acid (AKBA). This compound inhibits the action of 5-lipoxygenase, which is an enzyme involved in the biochemical cascade that leads to inflammation. Boswellia serrata Extract is regularly recommended to patients of osteoarthritis of the knee with possible therapeutic use in other arthritis.
Harpagophytum procumbens, is a perennial South African plant whose roots have long been known for their medicinal properties such as the ability to alleviate joint pain. Its active components are believed to be its iridoid glycosides, and in particular the monoterpene harpagoside. Many clinical trials have tested the validity of Harpagophytum procumbens as an anti-inflammatory and analgesic botanical, especially for relieving arthritic symptoms. Devil's claw supplementation has been consistently shown to be safe and effective for managing pain in patients suffering from knee or hip osteoarthritis and non-specific low back pain.
Ginger has been used in Chinese, Japanese, and Indian medicine for hundreds of years to decrease arthritis joint pain and inflammation. Modern scientific research has revealed that ginger possesses numerous therapeutic properties including antioxidant effects, an ability to inhibit the formation of inflammatory compounds, and direct anti-inflammatory effects. The roots and underground stems are the basis for powders, extracts, tinctures and oils. Ginger, like the NSAID's, inhibits the enzymes cyclooxygenase-1 and cyclooxygenase-2. (Cox 1 and 2).
The bark and root of yucca — a group of shrub-like plants native to the southwestern United States and Mexico have been used for centuries in traditional Native American medicine for joint health. The plant contains several physiologically active phytochemicals. It is a rich source of steroidal saponins, and is used commercially as a saponin source. Saponins have diverse biological effects, including anti-protozoal activity. It has been postulated that saponins may have anti-arthritic properties by suppressing intestinal protozoa which may have a role in joint inflammation. The yucca is also a rich source of polyphenolicshese, known to have anti-inflammatory activity. They are inhibitors of the nuclear transcription factor NFkappaB. NFkB stimulates synthesis of inducible nitric oxide synthase (iNOS), which causes formation of the inflammatory agent nitric oxide.
The bark of the white willow tree (Salix alba) has been used in China for centuries as a medicine because of its ability to relieve pain. Early settlers to America found Native Americans gathering bark from indigenous willow trees for similar purposes. The active ingredient in white willow is salicin, which the body converts into salicylic acid. The first aspirin (acetylsalicylic acid) was made from a different salicin-containing herb–meadowsweet–but works in essentially the same way. The salicylic acid in white willow bark lowers the body’s levels of prostaglandins, hormone-like compounds that can cause aches, pain, and inflammation. While white willow bark takes longer to begin acting than aspirin, its effect may last longer. And, unlike aspirin, it doesn’t cause stomach bleeding or other known adverse effects.